Increasing consumption of red meat increases
blood trimethylamine concentration. According to previous
research, a toxic substance increases the risk of cardiovascular
diseases. WHO experts intend to label red meat.
any kind of carcinogenic product.
Contents
Causes of red meat damage to the cardiovascular system
People who eat a lot of beef, veal, pork,
lamb are at increased risk of developing
атеросклеротических diseases.
Until 2017, the reasons were mainly
saturated fatty acids and cholesterol.
American explorer Stanley Hazen from Cleveland
the clinic, however, is convinced that the cause is carnitine. is he
is processed in the intestine by bacteria to trimethylamine. After
chemical absorption in the liver turns into oxide
trimethylamine (TMAO).
In previous studies, Hazen was able to show that TMAO levels
blood associated with an increased risk of cardiovascular
diseases. People with the highest concentrations are likely to
heart attack increased 2.5 times within 2 years.
However, it was unclear whether the diet is responsible for
increase in concentration of TMAO. Therefore, the researcher held
study with the US National Heart, Lung, and Blood Institute.
It was attended by 113 healthy men and women who had
meat based diet.
For 4 weeks, participants daily took meals from
steak (250 grams) or 2 hamburger with meatballs (250 grams). After
A 2-week period followed a 4-week diet with a high proportion
poultry meat. Then after 2 weeks, participants completely abandoned
meat
What results did scientists get?
Half of the participants had reduced the fat content in the diet, but
this did not affect the concentration of TMAO in plasma and urine.
According to the presented results, only the diet of red
meat has led to a 3-fold increase in the concentration of TMAO in plasma.
This increase was reversible. After перехода на птичью или
vegetarian diet TMAO immediately decreased.
TMAO was eliminated relatively quickly through the kidneys. Like this
accelerates the progression of atherosclerosis, it is unclear. Experts
suggest that TMAO may contribute to the inclusion of cholesterol in
vessel wall.
Does the diet protect against atherosclerosis?
Scientists do not know whether a vegetarian diet protects against
cardiovascular disease.
The proof will require longer interventional
tests that are very expensive and therefore are performed
seldom.
However, Hazen developed a drug that blocks enzymes.
intestinal bacteria involved in the formation of TMAO. In the spring
the researcher published in Nature the first experimental
results on animals.
A single dose reduced the plasma concentration of TMAO for 3
days Human clinical studies are still not
were carried out.
What do skeptics think about research on the harmfulness of meat?
Processed or smoked meat slightly increases the ubiquitous
age risk of cancer in humans. However, man is omnivorous; about
This is indicated by the muscles, intestinal, digestive and
excretory activity.
Homo sapiens comparable to highly developed primates
thanks to mixed and fruit based
diet
Мясо, рыба, птица, крупы и молочные продукты aboutязательно должны
enter the diet.
Energy requirements compared to proteins, carbohydrates,
fats, minerals and trace elements is much higher due to the development
the brain. Skeptics believe that people do not die directly from
meat, and from post-industrial poverty.
Фактически изaboutилие пищи увеличивает риск развития
obesity. 22 WHO experts say they can classify
неaboutработанное красное мясо как «вероятно
carcinogenic. “
Experts даже не могут доказать, что потребление красного мяса
is carcinogenic. Only 7 out of 15 informative studies
случай-контроль соaboutщают о положительной связи между смертностью и
meat
Due to the lack of statistically significant
evidence to make a conclusion about the harmfulness of meat for vessels and heart
definitely impossible. ВОЗ aboutъявляет, что в начале следующего года
комитет экспертов оценит новые результаты и их влияние на aboutщие
nutritional advice.
